Introduction

This module is based on the STRING database to automatically construct protein interaction networks for gene sets, supporting multiple clustering algorithms (GN/MCL/Kmeans), identifying functional modules, outputting gene clustering assignments and node connectivity (degree), and visualizing network structures, supporting further exploration in Cytoscape.

Reference

• Szklarczyk, D., Kirsch, R., Koutrouli, M., Nastou, K., Mehryary, F., Hachilif, R., ... & Von Mering, C. (2023). The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest. Nucleic acids research, 51(D1), D638-D646.